Definition
Phase 1 tests safety and blood levels in a few dozen people. Phase 2 looks for an effect and a dose in a few hundred. Phase 3 confirms it in hundreds to thousands, against a comparator, and is what regulators approve on. Retatrutide is in phase 3; most research-market peptides never entered phase 1.
Where it matters on LYO
- BRetatrutide3 phase 3 RCTs published (n=2,339; n=1,152; n=537); 2 phase 3 topline
- BCagrilintidePhase 3 published
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