Why it exists
Peptides are discussed everywhere and understood almost nowhere. Most of what is written about them either sells something or repeats someone who does, and the language of science — "studies show," "clinically proven" — is used freely without the studies behind it. The result is a reader who cannot tell a molecule with thirty randomised trials from one with none.
LYO's answer is to make the evidence itself the product. Each compound is broken into its claimed effects; each effect gets a grade that reflects only what has been shown in people; each grade points to the trials it rests on. The reader is left with a clearer question than they arrived with, and the means to answer it.
Scope
LYO covers regulatory status across the European Union, United States, United Kingdom, Australia and Canada, plus the WADA prohibited list, because those are the frameworks most readers fall under and they frequently disagree with each other. A compound approved in one is often unauthorised in the next — exactly the confusion the site exists to remove.
LYO describes what a compound is, what the evidence says, and where it stands legally. It does not publish doses, protocols, instructions for preparation or use, or information on where to obtain anything. That line separates a reference from a prescription, and LYO stays on the reference side of it.
How a page gets written
Each compound page starts with the primary literature — the trials themselves, not summaries of them — and a search of the registries for anything unpublished. Every claimed effect becomes a row on the evidence matrix with a grade, an effect size and the human studies behind it. The opening paragraph is written last, once the matrix exists, because it has to be defensible line by line. The full rules are on the methodology page.
Funding and disclosures
LYO currently has no revenue and no commercial relationships with any manufacturer, supplier or clinic. If that changes, it will be disclosed here and on every affected page before it takes effect. The data is published under CC BY 4.0 so the grades can be checked, reused and cited by anyone without asking.
Corrections
If a grade is wrong, the fastest way to fix it is the study that shows it. Corrections are logged on the affected page's change log, dated, and never made silently. Send one through the contact page; replies come by email and at a private link.
Research and educational use
Everything on LYO is published for research and educational purposes. It is not medical advice, not a recommendation to use any compound, and not a substitute for a clinician who knows your circumstances. Grades describe evidence, not what any individual should do with it.