Definition
The first summary of a trial's main results, released by the sponsor before the full data are published or peer-reviewed. Usually accurate on the headline number, silent on everything else. LYO grades outcomes resting on topline results no higher than B until the paper appears.
Where it matters on LYO
- BRetatrutide3 phase 3 RCTs published (n=2,339; n=1,152; n=537); 2 phase 3 topline
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