Does Thymalin help with independent replication?

What the studies show

LYO's search found no randomised trial of thymalin by any group outside the St Petersburg Institute of Bioregulation and Gerontology.

A few small or poorly-controlled human studies. Enough to be interesting; not enough to count on. Most of what gets called “clinically proven” online lives here.

1. 1
   PubMed search: thymalin randomized controlled trial — no independent RCT identified.PubMed, searched 2026-09-23

In context

Thymalin is a mixture of short peptides extracted from calf thymus, developed in Soviet-era St Petersburg and sold as an immune 'bioregulator'. The evidence behind its anti-ageing reputation is a 2003 report of 266 elderly people followed for six to eight years, which claims halved mortality but describes neither randomisation nor blinding. No trial outside that group's institute exists in the indexed literature. It is not approved in any region this site covers.

Thymalin is not approved (russia only). Legal status differs by country — see the regulation section or the jurisdiction pages.

Questions

Other outcomes for Thymalin

• CMortality in the elderly1 long-term series (n=266, 6–8 yr)
• CRespiratory infectionsSame series

Written and maintained by LYO Research — how pages are written and checked. Reviewed 23 September 2026. Grades count human evidence only; see how LYO grades. Not medical advice. Correct this page →