What the studies show
Licensed for hypogonadotropic hypogonadism, where it stimulates the testes directly; used clinically to maintain testicular function and fertility.
Several well-run randomised trials in people, pointing the same way. You can plan around this. It still says nothing about whether the effect is worth the side effects for you.
- 1Chorionic gonadotropin prescribing information and approved indications.FDA / EMA product informationFertility and hypogonadism indications; required weight-loss disclaimer.
In context
HCG is a hormone of pregnancy, approved to trigger ovulation in fertility treatment and to treat certain forms of low testosterone and undescended testicles. It is also the basis of the HCG diet, which pairs injections with a 500-calorie regime. A meta-analysis of the controlled trials found no evidence that HCG does anything at all for weight, hunger or fat distribution — any weight lost is caused by the starvation diet accompanying it.
HCG (human chorionic gonadotropin) is approved (rx) for fertility and hypogonadism; not for weight loss. Legal status differs by country — see the regulation section or the jurisdiction pages.
Questions
Is HCG (human chorionic gonadotropin) proven to help with testosterone stimulation in men?
What studies are behind the grade?
Is HCG (human chorionic gonadotropin) approved for this?
Other outcomes for HCG (human chorionic gonadotropin)
- AOvulation induction and fertilityApproval-grade programmes
- AWeight lossMeta-analysis of 8 controlled trials
Written and maintained by LYO Research — how pages are written and checked. Reviewed 3 September 2026. Grades count human evidence only; see how LYO grades. Not medical advice. Correct this page →