Claimed effect · Follistatin 344

Does Follistatin 344 help with fat loss?

D
Grade D — no human evidenceNone · effect size: not measurable
Short answerNo human evidence. As of 10 September 2026, only none exist for Follistatin 344 for fat loss. Claimed on the basis of myostatin-knockout animals; no human data.

What the studies show

Claimed on the basis of myostatin-knockout animals; no human data.

Animal studies, cell studies, or anecdotes only. This is where almost every viral peptide sits. Promising and proven are different words for a reason.

In context

Follistatin is a natural protein that binds and blocks myostatin, the signal that limits muscle growth; animals engineered to overexpress it become dramatically muscular. 'Follistatin 344' is the full-length form, sold as a lyophilised injectable for muscle. No human trial has ever tested injecting it. The only clinical data is a 2015 gene-therapy study in six men with Becker muscular dystrophy, in which a virus carrying the follistatin gene was injected into the thigh muscles — some walked further, some did not, and it is not the product being sold. It is prohibited in sport.

Follistatin 344 is not approved; research reagent. Legal status differs by country — see the regulation section or the jurisdiction pages.

Questions

Is Follistatin 344 proven to help with fat loss?
No. There is no human evidence for it (None); the claim rests on animal or cell studies and LYO grades it D.
What studies are behind the grade?
Claimed on the basis of myostatin-knockout animals; no human data.
Is Follistatin 344 approved for this?
No. Follistatin 344 is not approved; research reagent; it is not an approved medicine for any indication in the jurisdictions LYO covers.

Other outcomes for Follistatin 344

Written and maintained by LYO Research — how pages are written and checked. Reviewed 10 September 2026. Grades count human evidence only; see how LYO grades. Not medical advice. Correct this page →